The sAOP (stressor AOP) server is a resource for annotated AOPs (adverse outcome pathways) connected to toxic compounds from ToxCast. It is a compilation of more than 6000 chemical compounds annotated to the assay endpoints used for their detection, as well as more than 200 AOPs.
sAOP aids in the assessment of toxic and adverse events, and side effects. By integrating a dataset containing annotated bioassays for chemical risk assessment (drugs and environmental chemicals) and the OECD approved AOPs, this tools assists the researcher on the search for toxic compounds related to specific AOPs, assays to validate the toxic events and the already described adverse outcome pathways.
How to cite:
Alejandro Aguayo-Orozco, Karine Audouze, Troels Siggaard, Robert Barouki, Søren Brunak, Olivier Taboureau, sAOP: Linking chemical stressors to Adverse Outcomes Pathway Networks, Bioinformatics, , btz570,
https://doi.org/10.1093/bioinformatics/btz570